...

Retinoin Pm Treatment Serum – 1 oz

Retinoin Pm Treatment Serum – 1 oz

$112.00

2.5x $112 · 5x $116

An advanced retinol treatment serum with a patent-approved Active Pro-Penetrant delivery system, clinically studied head-to-head against prescription tretinoin and shown to be equivalent or better. Available in two strengths.

Who this is for:

Patients who have already built retinol tolerance and are ready for a more active retinization experience. Also ideal for anyone who has been told they need prescription tretinoin and wants to explore a non-prescription alternative with published clinical evidence. This is not a beginner retinol. It is a serious treatment serum for skin that is ready for it.

What it does:

  • Delivers prescription-level retinization results without a prescription, as demonstrated in a double-blind clinical study published in the Journal of Drugs in Dermatology
  • Outperformed prescription tretinoin on visible skin smoothness in the published study
  • Produced greater collagen formation on biopsy than prescription tretinoin at 12 weeks
  • Demonstrated 16% better barrier function than prescription tretinoin at 12 weeks
  • Showed less itching than prescription tretinoin, a statistically significant finding
  • Brightens and resurfaces simultaneously with Licorice Root targeting discoloration while retinol drives cell turnover
  • Reduces redness and boosts antioxidant activity with Bakuchiol, a natural retinol complement
Category

Description

Key ingredients:

  • All-trans Retinol: the most potent OTC retinoid form, used here at a more advanced concentration than the Gentle Retinol serum
  • Patent-Approved Active Pro-Penetrant Delivery System: ensures retinol reaches the target depth in the skin where it can do its most meaningful work
  • Bakuchiol: a natural ingredient derived from the Psoralea corylifolia seed with retinol-like gene expression activity. Reduces redness and boosts antioxidant protection alongside the retinol rather than competing with it.
  • Licorice Root: anti-inflammatory pigment control that brightens while the retinol resurfaces
  • Green Tea Polyphenols: antioxidant and calming support throughout the retinization process


How to use:

Apply one full pipette to clean, dry skin at night only. Begin every third night for the first two weeks, then every other night for the next two weeks, then every night as tolerated. Do not apply to wet skin. Follow immediately with the Lipid Replenishing Soft Cream. Always use SPF during the day. This serum is intended for patients who have already built tolerance on the Gentle Retinol or an equivalent retinol product.

Good to know:

✓ Fragrance free ✓ Oil free ✓ Gluten free ✓ Paraben free ✓ Patent-approved delivery system ✓ Published in the Journal of Drugs in Dermatology ✓ Clinically studied against prescription tretinoin: equivalent or better results ✓ Available in 2.5x and 5x strengths ✓ Physician-curated ✓ Step 5 of your routine (after moisturizer, last step at night)

Some dryness, redness, or flaking during the first few weeks is completely normal and expected. It is a sign your skin is retinizing. The remedy is simple: use our Lipid Replenishing Soft Cream on top every night. It was the moisturizer used alongside this exact serum in the clinical study.

This is the retinol that was studied head-to-head against prescription tretinoin in a published peer-reviewed clinical trial and came out equivalent or better. If you have ever been told you need a prescription retinoid, this is worth knowing about. Once you have been consistently tolerating the 5x strength, Dr. Milman will check in with you at your next visit to discuss whether any further escalation makes sense for your skin.

Call Now Button